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Scientific Studies

Picrorhiza kurroa – tradition confirmed

Picrorhiza kurroa – tradition confirmed



Picrorhiza kurroa known as Katuki in traditional Ayurvedic medical system, was used for thousands of years for liver and bile diseases.

It’s a little herb that is found in regions of average height (3000 – 5000 m) in the Himalayas. Rhizomes and roots are the plant parts that concentrates the majority of its active ingredients. Recent researches have focused particularly on demonstrating hepatoprotective, anticholestatic, antioxidant and immunomodulatory effects of Picrorhiza kurroa constituents.

The main active substances identified in this plant are kutkin, apocynin, drosin and nine cucurbitanoid glycosides. Apocynin has anti-inflammatory effect by inhibiting the release of proinflammatory substances by neutrophils, reducing the chances of liver fibrosis after an infectious episode.

Picrorhiza kurroa provides good protection against various types of liver toxic assaults. Researchers have demonstrated that liver damage was minimal, basically not being able to detect major histological or biochemical changes in intoxication with various hepatotoxic substances (aflatoxin B1, Galactosamine, tiocetamide, carbon tetrachloride, etc.), as long as it was co-administered with Picrorhiza kurroa extract (25 mg / kg / day). This is due to kutkin in its composition which has been shown to affect the liver cell membrane structure so that prevents toxins to enter in the liver cells.

Picrorhiza kurroa standardized extract is one of the most important extracts contained in Hepaid Forte, significantly contributing to superior clinical outcomes for effective liver protection, acting complementary with the other 19 extracts contained in this product. The conclusions of the current studies shows that modern science confirms the traditional use of Picrorhiza kurroa extract in poliherbal hepatoprotective preparations, with outstanding efficiency at liver level, maintaining liver health.

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Hepaid Forte administered at a dose of 2 capsules per day, is thus beneficial for:

Protecting and supporting the liver under stress, fatigue, pollution, unbalanced diet, rich in fats;

Support normal functioning of the liver;

Protection of liver cells;

Supporting the natural regeneration of liver cells;

Improvement in digestion and metabolism.